Leptomeningeal Metastases

نویسندگان

  • LISA BOMGAARS
  • MARC C. CHAMBERLAIN
  • DAVID G. POPLACK
  • SUSAN M. BLANEY
چکیده

1. Carcinomatous meningitis (metastases caused by carcinoma such as lung and breast) 2. Meningeal gliomatosis (dissemination of CSF caused by malignant glial tumors) 3. Leptomeningeal metastases secondary to other underlying solid tumors (e.g., rhabdomyosarcoma, neuroblastoma, medulloblastoma, other primitive neuroectodermal tumors) 4. Lymphomatous meningitis (metastases caused by lymphoma) 5. Leukemic meningitis (metastases caused by leukemia) (Chamberlain, 1992; Grossman and Moynihan, 1991; Kaplan et al., 1990; Little et al., 1974; Olson et al., 1974; Packer et al., 1985; Shapiro et al., 1977; Theodore and Gendelman, 1981; Wasserstrom et al., 1982; Yung et al., 1980).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

MR imaging of leptomeningeal metastases: comparison of three sequences.

BACKGROUND AND PURPOSE Recent work has shown that fluid-attenuated inversion recovery (FLAIR) imaging with contrast enhancement is highly sensitive for detecting subarachnoid space disease. We hypothesized that contrast-enhanced FLAIR imaging has superior sensitivity to contrast-enhanced T1-weighted MR imaging in detecting leptomeningeal metastases. METHODS Sixty-eight patients referred for s...

متن کامل

A case of brain and leptomeningeal metastases from urothelial carcinoma of the bladder.

Brain metastases are unusual from urethelial carcinoma of bladder and particularly the occurrence of leptomeningeal metastases is extremely rare, with few cases described in the literature. We present a case of a 45-year-old man with a rare brain metastases as the first metastatic manifestation secondary to urethelial carcinoma of bladder followed by leptomeningeal metastases without any other ...

متن کامل

The prognostic significance of surgically treated hydrocephalus in leptomeningeal metastases

OBJECTIVE The median survival of leptomeningeal metastases is short despite therapy and is sometime associated with hydrocephalus. We investigated the prognostic significance of surgically treated hydrocephalus in leptomeningeal metastases. MATERIALS AND METHODS Between December 2005 and November 2012, 1343 patients had brain metastases from systemic solid tumors. Of these, 71 patients (5.3%)...

متن کامل

Management of Leptomeningeal Disease From Solid Tumors.

Leptomeningeal carcinomatosis, known by a variety of names, including leptomeningeal metastases and neoplastic meningitis, indicates spread of tumor to the cerebrospinal fluid (CSF) and invasion of the subarachnoid space. The term leptomeningeal (from the Greek lepto, meaning “fine” or “slight”) describes the thin meninges, the arachnoid and the pia mater, between which the CSF is located. Alth...

متن کامل

High-dose, pulsatile erlotinib in two NSCLC patients with leptomeningeal metastases--one with a remarkable thoracic response as well.

A considerable number of patients with epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) develop leptomeningeal metastases. Leptomeningeal metastases are associated with deterioration of clinical symptoms and poor survival. Traditionally, treatment of metastases in the central nervous system consists of radiotherapy and less frequently, surgery. The role of syst...

متن کامل

Cyberknife Radiosurgery and Concurrent Intrathecal Chemotherapy for Leptomeningeal Metastases: Case Report of Prolonged Survival of a HER-2+ Breast Cancer Patient Status-Post Craniospinal Irradiation

Leptomeningeal disease (LMD) from breast cancer is usually a rapidly fatal condition, with median overall survival reported to be 15 weeks. Conventional treatment for LMD includes craniospinal irradiation and intrathecal (IT) methotrexate. However, the role of stereotactic radiation for leptomeningeal disease remains poorly defined. This case report describes our experience using Cyberknife rad...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2002